Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764578 | Biochemical and Biophysical Research Communications | 2011 | 4 Pages |
Abstract
⺠Telmisartan was the strongest ARB for the reduction of BP in patients with essential hypertension. ⺠Telmisartan had a unique binding mode to the AT1 receptor due to its distal benzimidazole portion. ⺠Due to its “delta lock” structure, telmisartan may be superior to other ARBs in halting cardiovascular disease in patients with hypertension.
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Authors
Kazuki Ohno, Yasushi Amano, Hirotoshi Kakuta, Tatsuya Niimi, Shoji Takakura, Masaya Orita, Keiji Miyata, Hitoshi Sakashita, Makoto Takeuchi, Issei Komuro, Jitsuo Higaki, Masatsugu Horiuchi, Shokei Kim-Mitsuyama, Yutaka Mori, Ryuichi Morishita,