| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764583 | Biochemical and Biophysical Research Communications | 2011 | 5 Pages |
Abstract
⺠Methylmalonyl-CoA mutase (MCM) undergoes oxidative inactivation during catalysis. ⺠mut and MMAA gene mutations generate a rare disorder called methylmalonic acidemia. ⺠Bacterial reactivases restore the activity of inactivated AdoCbl-dependent enzymes. ⺠We demonstrate that the function of MMAA protein is to protect/reactivate inactive MCM.
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Authors
Tóshiko Takahashi-Íñiguez, Humberto GarcÃa-Arellano, Mauricio A. Trujillo-Roldán, MarÃa Elena Flores,