Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764605 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Serine/threonine protein phosphatase 5 (PP5) has been shown to participate in ataxia telangiectasia-mutated (ATM)- and ATR (ATM- and Rad3-related)-mediated checkpoint pathways, which plays an important role in the DNA damage response and maintenance of genomic stability. ⺠However, it is not clear exactly how PP5 participates in this process. ⺠Our results indicate that PP5 is more closely related with ATR-mediated pathway than ATM-mediated pathway in DNA damage repair.
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Authors
Yoonsung Kang, Hyang-Min Cheong, Jung-Hee Lee, Peter I. Song, Kwang-Ho Lee, Sang-Yong Kim, Jae Yeoul Jun, Ho Jin You,