| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764614 | Biochemical and Biophysical Research Communications | 2011 | 6 Pages |
Abstract
⺠Synemin and plectin are cross-linking proteins which mediate the interaction between intermediate filament and other cytoskeletal networks. ⺠The expression of synemin was down-regulated in human hepatocellular carcinoma tissues. ⺠Synemin knock-down did not influence the cytoskeleton expression and organization of human Chang liver cells. ⺠The function of synemin in liver cells would then be more like a cytoskeletal component, not a cross-linking protein.
Keywords
IFAPPBSDMEMSDSFITCFCSPVDFHRPHCCDulbecco’s modified Eagle mediumPlectinSmall interfering RNAsiRNAintermediate filamentMicrotubulesodium dodecyl sulfatefetal calf serumcytokeratinSyneminPhosphate buffered salineMicrofilamentHorseradish peroxidasePolyvinylidene fluorideCytoskeletonHepatocellular carcinoma
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Authors
Yi-Hsiang Liu, Chiung-Chi Cheng, Yih-Shyong Lai, Wei-Ting Chao, Ren-Jeng Pei, Yung-Hsiang Hsu, Chin-Chin Ho,