| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764657 | Biochemical and Biophysical Research Communications | 2010 | 6 Pages |
Abstract
⺠Ascochlorin, an isoprenoid antibiotic, induces G1 arrest in human cancer cells. ⺠Activation of p21WAF1/CIP1 by ascochlorin, a non-toxic anti-cancer agent, is dependent on c-Myc, and not p53. ⺠Ascochlorin inhibits the phosphorylation of pRB and represses E2F1 transcriptional activity.
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Authors
Ji-Hak Jeong, Young-Chae Chang,