| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764759 | Biochemical and Biophysical Research Communications | 2010 | 6 Pages |
Abstract
⺠Antimicrobial peptide, hominicin, was purified from culture supernatant of Staphylococcus hominis MBBL 2-9. ⺠Hominicin exhibited potent activity against several Gram-positive and antibiotic-resistant pathogens. ⺠Hominicin exhibited heat stability up to 121 °C for 15 min and activity under both acidic and basic conditions (from pH 2.0 to 10.0). ⺠The sequence of hominicin was revealed as DmIle-Dhb-Pro-Ala-Dhb-Pro-Phe-Dhb-Pro-Ala-Ile-Thr-Glu-Ile-Dhb-Ala-Ala-Val-Ile-Ala-Dmp. ⺠Hominicin is a novel antimicrobial peptide, which has uncommon amino acid residues like the ones in Class I group, but without thioether bridge.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Pyoung Il Kim, Jae Kyung Sohng, Changmin Sung, Hwang-Soo Joo, Eun-Mi Kim, Tokutaro Yamaguchi, Daejoong Park, Byung-Gee Kim,