Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764760 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠Polynitroxylated hemoglobin (Hb) in oxidized and reduced forms exhibit peroxidase activity. ⺠In plasma, ascorbate reduces polynitroxylated Hb. ⺠Elimination of H2O2 by reduced polynitroxylated Hb is at the expense of its reduced nitroxides. ⺠Both forms of polynitroxylated Hb protect SH-SY5Y cells from H2O2 toxicity.
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Authors
Detcho A. Stoyanovsky, Alexandr Kapralov, Zhentai Huang, Akihiro Maeda, Anatoly Osipov, Carleton J.C. Hsia, Li Ma, Patrick M. Kochanek, Hulya Bayr, Valerian E. Kagan,