| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764764 | Biochemical and Biophysical Research Communications | 2010 | 7 Pages |
Abstract
⺠Mouse PDX1 Ser-269 is phosphorylated in pancreatic islets of Langerhans and beta cells. ⺠High glucose concentration decreases the degree of phosphorylation on PDX1 Ser-269, as assessed by a phospho-specific anti-phospho-Ser269 antibody. ⺠HIPK2 is a potential kinase for PDX1 Ser-269. ⺠Phosphorylation at Ser-269 affects the subnuclear distribution of PDX1.
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Authors
Rong An, Gabriela da Silva Xavier, Francesca Semplici, Saharnaz Vakhshouri, Huai-Xiang Hao, Jared Rutter, Mario A. Pagano, Flavio Meggio, Lorenzo A. Pinna, Guy A. Rutter,