| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764776 | Biochemical and Biophysical Research Communications | 2010 | 6 Pages |
Abstract
⺠Loss of a guanine base does not hinder the formation of G-quadruplex of human telomere sequence. ⺠Each depurination strongly destabilizes the quadruplex of dG3(TTAG3)3 in NaCl and KCl. ⺠Conformational change of the abasic analogs of dG3(TTAG3)3 is inhibited in KCl. ⺠The effects abasic sites may affect telomere-end structures in vivo.
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Authors
Petra Å koláková, Klára BednáÅová, Michaela VorlÃÄková, Janos Sagi,