| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10764797 | Biochemical and Biophysical Research Communications | 2010 | 6 Pages |
Abstract
⺠Laminar shear stress phosphorylates Tyr-576 in FAK. ⺠XIAP is essential for shear stress-induced phosphorylation of Tyr-576. ⺠XIAP knockdown induces shear stress-triggered translocation of FAK into nucleus. ⺠XIAP regulates ERK activation by maintaining the Src-accessible location of FAK.
Keywords
ECMDCABAECXIAPPP2eNOSHUVECFAKSRCERKSmall interfering RNAsiRNADeoxycholic acidShear stressCAMbovine aortic endothelial cellHuman umbilical vein endothelial cellEndothelial cellsendothelial nitric oxide synthaseExtracellular matrixCell adhesion moleculeNitric oxidemitogen activated protein kinaseFocal adhesionMAP kinaseextracellular signal-regulated kinasefocal adhesion kinase
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Authors
Sunyoung Ahn, Heonyong Park,