Article ID Journal Published Year Pages File Type
10764906 Biochemical and Biophysical Research Communications 2010 7 Pages PDF
Abstract
► Depletion of kendrin induces centrosome splitting. ► Kendrin associates with Nek2A kinase exhibiting considerably low activity. ► Nek2A kinase activity is suppressed by direct binding with kendrin. ► Expression of the Nek2A binding site suppresses the centrosome splitting at G2 phase.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
Involvement of a centrosomal protein kendrin in the maintenance of centrosome cohesion by modulating Nek2A kinase activity
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