Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10764961 | Biochemical and Biophysical Research Communications | 2010 | 5 Pages |
Abstract
⺠Food protein derived bitter TRIPEPTIDES activate the human bitter receptor T2R1. ⺠Peptides with ACE-inhibitory activity were also able to activate the T2R1 receptor. ⺠Molecular modeling studies show T2R1 receptor has one binding site for agonist ligands. ⺠We identify amino acid residues on T2R1 important for ligand binding.
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Authors
Jasbir Upadhyaya, Sai Prasad Pydi, Nisha Singh, Rotimi E. Aluko, Prashen Chelikani,