Article ID Journal Published Year Pages File Type
10765514 Biochemical and Biophysical Research Communications 2010 6 Pages PDF
Abstract
Diabetes stimulates the expression of SR-BI in macrophages and leads to a shift in its activity from HDL-mediated cholesterol efflux to HDL-mediated cholesterol influx. These effects may lead to increased foam cell formation and atherosclerosis development.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Preview
High glucose stimulates macrophage SR-BI expression and induces a switch in its activity from cholesterol efflux to cholesterol influx
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