| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10765568 | Biochemical and Biophysical Research Communications | 2009 | 7 Pages |
Abstract
ANG-(1-7) decreases the amount of vascular remodeling, including a reduction in neointimal formation and collagen synthesis, after angioplasty in rabbits. The responsible mechanism may function through the possible down-regulation of TGF-β1 levels and inhibition of the Smad2 pathway.
Keywords
ARBrennin-angiotensin systemp-Smad2A-779VSMCsECMISRACE-IRASEELIELTGF-β1Angiotensin receptor antagonistangiotensinAngiotensin converting enzyme inhibitorsIn-stent restenosisAngVascular remodelingtransforming growth factor-betaTransforming growth factor-beta1Vascular smooth muscle cellsexternal elastic laminaExtracellular matrixHematoxylin and Eosin
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Authors
Wutao Zeng, Weiyan Chen, Xiuyu Leng, Jian gui He, Hong Ma,