| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10765696 | Biochemical and Biophysical Research Communications | 2009 | 5 Pages |
Abstract
Accumulating evidence indicates that various aspects of angiogenesis, such as proliferation, migration, and morphogenesis of endothelial cells, can be regulated by specific miRNAs in an endothelial-specific manner. As novel molecular targets, miRNAs have a potential value for treatment of angiogenesis-associated diseases such as cancers, inflammation, and vascular diseases. In this article, we review the latest advances in the identification and validation of angiogenesis-regulatory miRNAs and their targets, and discuss their roles and mechanisms in regulating endothelial cell function and angiogenesis.
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Authors
Fusheng Wu, Zeran Yang, Guohong Li,