| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10768178 | Biochemical and Biophysical Research Communications | 2005 | 6 Pages |
Abstract
P450 enzyme models carrying a SO3â ligand coordinating to iron have been synthesized and characterized. These complexes show characteristics very similar to those of iron-heme cofactors of P450 enzymes. Their reactivity towards different reactions catalyzed by P450 enzymes such as epoxidation of double bonds, hydroxylation of non-activated C-H bonds, N-dealkylation of amines, and cleavage of diols (C-C-bond cleavage) has been investigated.
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Authors
Dominik Meyer, Tycho Leifels, Laura Sbaragli, Wolf-D. Woggon,