Article ID Journal Published Year Pages File Type
10769501 Biochemical and Biophysical Research Communications 2005 8 Pages PDF
Abstract
Targeting the TEM-8 gene by way of a hammerhead ribozyme knocks out TEM-8 cells, and is an effective way to reduce the micro-vessel formation or migration potential in tumour-associated endothelial cell through its vW domain. These results suggest that the vW domain together with the transmembrane domain of TEM-8 may play an important biological role in TEM-8 related tubule formation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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