Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10769501 | Biochemical and Biophysical Research Communications | 2005 | 8 Pages |
Abstract
Targeting the TEM-8 gene by way of a hammerhead ribozyme knocks out TEM-8 cells, and is an effective way to reduce the micro-vessel formation or migration potential in tumour-associated endothelial cell through its vW domain. These results suggest that the vW domain together with the transmembrane domain of TEM-8 may play an important biological role in TEM-8 related tubule formation.
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Authors
K.A. Rmali, M.C.A. Puntis, W.G. Jiang,