| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10770345 | Biochemical and Biophysical Research Communications | 2005 | 5 Pages |
Abstract
We report here a novel carrier of quantum dots (QDs) for intracellular labeling. Monodisperse hybrid nanoparticles (38Â nm in diameter) of QDs were prepared by simple mixing with nanogels of cholesterol-bearing pullulan (CHP) modified with amino groups (CHPNH2). The CHPNH2-QD nanoparticles were effectively internalized into the various human cells examined. The efficiency of cellular uptake was much higher than that of a conventional carrier, cationic liposome. These hybrid nanoparticles could be a promising fluorescent probe for bioimaging.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Urara Hasegawa, Shin-ichiro M. Nomura, Sunil C. Kaul, Takashi Hirano, Kazunari Akiyoshi,