| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797022 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 10 Pages |
Abstract
⺠We use MD and DSC to examine the effects of xenon on lipid membranes. ⺠Xenon atoms preferentially localize in the hydrophobic core of the lipid bilayer. ⺠Xenon induces substantial structural changes in the lipid bilayers. ⺠Xenon depresses the membrane gel-liquid crystalline phase transition temperature. ⺠Our results are consistent with a lipid bilayer-mediated mechanism of anesthesia.
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Authors
Ryan D. Booker, Amadeu K. Sum,