Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797090 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 10 Pages |
Abstract
⺠Gap junction communication is crucial for myelination and axonal survival in the PNS and CNS. ⺠Gap junctions form a panglial syncytium between oligodendrocytes and astrocytes. ⺠They couple groups of cells together generating communication compartments. ⺠Connexons contribute to extracellular signaling via release of neurotransmitters. ⺠Mutations in connexin proteins change the properties and regulation of gap junctions.
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Authors
Anna Nualart-Marti, Carles Solsona, R. Douglas Fields,