Article ID Journal Published Year Pages File Type
10797092 Biochimica et Biophysica Acta (BBA) - Biomembranes 2013 15 Pages PDF
Abstract
► Pannexin and connexin hemichannels represent an important route for ATP release. ► Purinergic P2Y receptors activate hemichannels to propagate inter-cellular calcium waves. ► P2X7 receptors activate multiple cell permeabilization pathways, including pannexin-1 hemichannels. ► Purinergic activation of hemichannels could represent a novel permeation pathway for different signaling metabolites.
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