| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797164 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 8 Pages |
Abstract
⺠In erythrocytes, lipid rafts are anchored to the spectrin skeleton in a carbonate-sensitive manner. ⺠The palmitoylated protein p55 could contribute to this anchoring via its palmitate. ⺠p55 palmitoylation was studied with an Ï-alkynyl analogue of palmitic acid and click chemistry. ⺠Carbonate does not depalmitoylate p55 but releases lipid rafts from membrane-skeleton. ⺠2-bromopalmitate and cerulenin inhibit p55 palmitoylation without affecting lipid raft anchoring.
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Authors
Annarita Ciana, Cesare Achilli, Rami N. Hannoush, Angela Risso, Cesare Balduini, Giampaolo Minetti,