Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797190 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 8 Pages |
Abstract
⺠Pyrene was simulated in POPC bilayers with variable amounts of cholesterol (Chol). ⺠Effects of pyrene on the bilayer structure and dynamics are globally small. ⺠Pyrene locates in the upper acyl chain region, and orders acyl chains in pure POPC. ⺠However, pyrene locally disorders Chol-rich bilayers, opposing the effect of Chol. ⺠The bilayer polarity sensed by the pyrene Ham effect is more precise than expected.
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Authors
LuÃs M.S. Loura, António M.T. Martins do Canto, Jorge Martins,