Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797199 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 6 Pages |
Abstract
⺠The antifungal effect of dioscin was investigated. ⺠The effect of dioscin on Candida albicans membrane was identified. ⺠Dioscin exerted antifungal effect via membrane disruption, resulting in cell death.
Keywords
3,3′-dipropylthiacarbocyaninebis-(1,3-dibutylbarbituric acid) trimethine oxonolDioscorea nipponicaLUVsDioscinGUV3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromideDiBAC4(3)DiSC3(5)MTTIndium tin oxideITOlarge unilamellar vesiclesGiant unilamellar vesiclephosphatidylinositolphosphatidylcholinephosphatidylethanolamineAntifungal activityMechanism
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Authors
Jaeyong Cho, Hyemin Choi, Juneyoung Lee, Mi-Sun Kim, Ho-Yong Sohn, Dong Gun Lee,