| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797206 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 8 Pages |
Abstract
⺠Neuronal CaV channels are implicated in neurological and psychiatric diseases. ⺠Cacna1 genes can generate many CaV channel isoforms through alternative splicing. ⺠Cell-specific splicing factors control the pool of CaV mRNA splice isoforms. ⺠Individual splicing events impact cell function and behavior. ⺠Expression of CaV splice isoforms can influence drug efficacy and disease severity.
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Authors
Diane Lipscombe, Arturo Andrade, Summer E. Allen,