| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797216 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2013 | 11 Pages |
Abstract
⺠This article reviews the dual functions of the skeletal muscle L-type Ca2 + channel. ⺠CaV1.1 is the voltage sensor for excitation-contraction coupling in skeletal muscle. ⺠CaV1.1 also conducts L-type Ca2 + current. ⺠Mutations in CaV1.1 have been linked to episodic muscle disorders. ⺠A CaV1.1 variant is involved in development and contributes to myotonic dystrophy 1.
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Authors
Roger A. Bannister, Kurt G. Beam,