Article ID Journal Published Year Pages File Type
10797222 Biochimica et Biophysica Acta (BBA) - Biomembranes 2013 15 Pages PDF
Abstract
► CaV2 channels play pivotal roles in neurotransmitter and hormone release. ► G protein coupled receptors orchestrate precise control of CaV2 channels. ► Voltage-dependent inhibition is mediated by direct binding of Gβγ to the channels. ► Voltage-independent inhibition is mediated by several other distinct pathways. ► Current understanding of these important mechanisms is provided in this review.
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