Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797248 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 10 Pages |
Abstract
âºThe manuscript gives an overview of biophysical and biochemical properties of aldehydophospholipid-protein adducts. âºAldehydophospholipids affect the physiological functions of atherogenic and antiatherogenic lipoproteins. âºAldehydophospholipids target many cellular proteins apart from classical lipid and lipoprotein receptors. âºAldehydophospholipid-protein adducts elicit autoimmune responses.
Keywords
VSMCPGPCPONPCPoxnoPC1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholinePLPCLipid toxicityPazePCMDAPOVPCOxPLoxLDLHNETLRPLAHDLBSAROSAtherosclerosisbovine serum albuminpoly unsaturated fatty acidPUFAHAECinterleukinToll-like receptorVascular smooth muscle cellshuman aortic endothelial cellsPlatelet activating factorphosphatidylcholinephosphatidylethanolaminePhosphatidylserinephospholipase AOxidized phospholipidoxidized phospholipidshigh density lipoproteinoxidized low density lipoproteinOxidized lipoproteinslow density lipoproteinLDLmalondialdehydePAFReactive oxygen species
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Authors
Ute Stemmer, Albin Hermetter,