| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797249 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 10 Pages |
Abstract
⺠The manuscript gives a concise overview of oxidized phospholipid biophysics. ⺠Biophysics of oxidized phospholipids explains the lipid binding of cytochrome c. ⺠Biophysics of oxidized lipids can explain enhanced amyloid fibril formation. ⺠We explain the correlations between neurodegenerative disorders, 2DM, and cancer.
Keywords
NBDRPECyt CMPTFAFAMDA2EIAPPAβHDPOxPLPazePCAMPTLCLIDCP1-palmitoyl-2-azelaoyl-sn-glycero-3-phosphocholineCMCPoxnoPCROSAmyloidapoapolipoproteinPUFAMisfoldingmitochondrial permeability transitionretinal pigment epitheliumLewy bodyAlzheimer's diseaseParkinson's diseaseBiomembraneprotein aggregationType 2 diabetesage-related macular degenerationcytochrome cSynSynucleincritical micelle concentrationOxidized phosphatidylcholineOxidized phospholipidoxidized phospholipidsAntimicrobial peptidesReactive oxygen species
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Authors
Paavo K.J. Kinnunen, Kai Kaarniranta, Ajay K. Mahalka,