Article ID Journal Published Year Pages File Type
10797270 Biochimica et Biophysica Acta (BBA) - Biomembranes 2012 7 Pages PDF
Abstract
► MSP2 is a clinically validated candidate for inclusion in a vaccine against malaria. ► We present a detailed structural characterisation of the lipid interactions of MSP2. ► Lipid interactions induce helical structure in the conserved N-terminal region. ► May modulate immune recognition and the immunodominance of the variable region. ► implications of GPI anchoring for properties of malaria antigens.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
Authors
, , , ,