Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797270 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 7 Pages |
Abstract
⺠MSP2 is a clinically validated candidate for inclusion in a vaccine against malaria. ⺠We present a detailed structural characterisation of the lipid interactions of MSP2. ⺠Lipid interactions induce helical structure in the conserved N-terminal region. ⺠May modulate immune recognition and the immunodominance of the variable region. ⺠implications of GPI anchoring for properties of malaria antigens.
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Authors
Christopher A. MacRaild, Marie Ã. Pedersen, Robin F. Anders, Raymond S. Norton,