Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797281 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 12 Pages |
Abstract
⺠DEER and Monte Carlo (MC) simulations reveal self-assembly of MBP on membranes. ⺠Singly spin-labeled MBPs exhibit short intermolecular distances on the membranes. ⺠Distances are shorter than for random distribution indicating membrane self-assembly. ⺠DEER data are analyzed using MC simulations of ellipses on a surface. ⺠Generalized approach: combine local DEER data and low-resolution MC interpretation.
Keywords
LPRMBPDSPGDSPCIDPMLVESEdistearoylphosphatidylcholineX-bandlarge unilamellar vesicleEPRElectron paramagnetic resonanceDistearoylphosphatidylglycerolDouble electron–electron resonanceLUVContinuous-waveMultiple sclerosisMyelinLipid-to-protein ratioMultilamellar vesicleMembrane proteinIntrinsically disordered proteinMyelin basic proteinDeer
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Authors
Daniel R. Kattnig, Timo Bund, Joan M. Boggs, George Harauz, Dariush Hinderberger,