| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797288 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 11 Pages |
Abstract
⺠Crotamine and NrTPs strongly interact with membrane model systems. ⺠Translocation is independent of specific receptors or electrochemical gradient. ⺠The same new microscopy methodology may test the translocation of other molecules. ⺠NrTPs acquire a partial helical structure upon binding to membranes. ⺠NrTPs are promising therapeutic tools for delivery of biomolecules or nanoprobes.
Keywords
6-aminohexanoic acid16-NS5-NSDPPEPOPGCrotaminerHbNBDDLSFMOCPoPCGUVAMPHEPESnuclear magnetic resonance1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid9-fluorenylmethoxycarbonylCPPsAhx16-doxyl-stearic acid5-doxyl-stearic acidMembrane translocationlarge unilamellar vesiclesNMRcircular dichroismRhodamine BGiant unilamellar vesiclesFluorescence spectroscopyLUVMembrane partitionDynamic Light ScatteringCell-penetrating peptideAntimicrobial peptideCell penetrating peptidesHPLChigh-performance liquid chromatography
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Authors
Margarida Rodrigues, Andrea Santos, Beatriz G. de la Torre, Gandhi Rádis-Baptista, David Andreu, Nuno C. Santos,