| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797329 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 10 Pages |
Abstract
⺠Physicochemical properties and biological activity of anionic lipoplexes correlated. ⺠Physicochemical studies were pivotal in formulation optimization for high silencing. ⺠Formulation components (lipid, Ca) contributed to serum stability and siRNA loading. ⺠Structural model of lipoplexes correlated to activity for different formulations. ⺠Information generated will be useful for product optimization and consistency.
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Authors
Mamta Kapoor, Diane J. Burgess,