Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797333 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 9 Pages |
Abstract
⺠Asymmetric liposome particles (ALPs) with highly efficient siRNA encapsulation and negatively charged surface. ⺠The ALPs protect the encapsulated siRNA from RNase A. ⺠The cellular uptake of ALPs is only induced by attachment of ligands interacting with cell surface receptors. ⺠The internalized siRNA successfully inhibits the target gene expression.
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Authors
Amir Abbas Mokhtarieh, Sinyoung Cheong, Semi Kim, Bong Hyun Chung, Myung Kyu Lee,