| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797350 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 11 Pages |
Abstract
âºCoupling between voltage-sensing and pore domains in a Kv channel is studied by MD. âºRestraints based on experimental data are used to move the voltage-sensing domains. âºFull channel closure required additional lateral and inward motion of the VSDs. âºAn all-atom closed/resting state of the KvAP channel was produced by this work.
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Authors
Eric V. Schow, J. Alfredo Freites, Alex Nizkorodov, Stephen H. White, Douglas J. Tobias,