| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797351 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 8 Pages |
Abstract
⺠KAAT1 Gly 85-87 mutants are expressed on the membrane surface although at different level. ⺠Mutants showed altered interaction with cations. ⺠Cross-linking of cysteine mutants by oxidative treatment inhibited transport activity. ⺠Na+ protected position 87 from oxidation both directly and indirectly. ⺠Glycine flexibility is involved in KAAT1 function and its interaction with cations.
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Authors
M. Giovanola, F. D'Antoni, M. Santacroce, S.A. Mari, F. Cherubino, E. Bossi, V.F. Sacchi, M. Castagna,