Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797354 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 9 Pages |
Abstract
⺠Two cell penetrating peptides with opposite cell uptake capacities are investigated. ⺠Their binding, insertion and perturbation of model membranes are studied. ⺠The peptides share many similarities regarding lipid membrane interaction. ⺠Subtle differences concern insertion depth, effect on lipid ordering and kinetics. ⺠Some peptide molecules flipped their orientation with arginines serving as hinges.
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Authors
Astrid Walrant, Alexander Vogel, Isabelle Correia, Olivier Lequin, Bjoern E.S. Olausson, Bernard Desbat, Sandrine Sagan, Isabel D. Alves,