Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797371 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 10 Pages |
Abstract
⺠Connexins have high turnover rates in most tissue types. ⺠Multiple pathways exist for post-endocytic sorting of connexins to lysosomes. ⺠Degradation of connexins is regulated by phosphorylation and ubiquitination.
Keywords
PKCearly endosomal autoantigen 1DAB2TSG101NRKNedd4HECTESCRTZO-1SCFEEA1EGFGPCRHRSERAD12-O-tetradecanoylphorbol-13-acetatetPAENaCMAPKPtdIns(4,5)P2EndocytosisChoChinese Hamster Ovaryendoplasmic reticulum-associated degradationDegradationRingHepatocyte growth factor-regulated tyrosine kinase substratezonula occludens 1epidermal growth factorgap junctionphosphatidylinositol 4,5-bisphosphateLysosomeendosomal sorting complex required for transportDisabled-2Protein kinase Cmitogen-activated protein kinasereally interesting new genenormal rat kidneyconnexinG protein-coupled receptorUbiquitin
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Authors
Edward Leithe, Solveig Sirnes, Tone Fykerud, Ane Kjenseth, Edgar Rivedal,