| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797419 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 9 Pages |
Abstract
⺠KCNH1 potassium channels are exceptionally sensitive to oxidative modification. ⺠Thiol-dependent modification of channel gating occurs in two different ways. ⺠C145/C214 in the N-linker are responsible for fast modification. ⺠C532/C562 in the C-linker are responsible for slow modification. ⺠Redox regulation determines information flow from the cytosolic termini to the channel's gate.
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Authors
Nirakar Sahoo, Roland Schönherr, Toshinori Hoshi, Stefan H. Heinemann,