| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797512 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 7 Pages |
Abstract
⺠hOCTN1 transporter reconstituted in liposomes catalyzes acetylcholine transport. ⺠The transporter in proteoliposome has the same orientation as in cell membrane. ⺠Transport occurs as uptake or efflux from proteoliposomes (cells). ⺠Efflux is physiologically related to the non-neuronal acetylcholine system. ⺠Acetylcholine efflux is defective in the Crohn's disease associated L503F mutant.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Lorena Pochini, Mariafrancesca Scalise, Michele Galluccio, Giovambattista Pani, Katherine A. Siminovitch, Cesare Indiveri,