| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797520 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 9 Pages |
Abstract
⺠Selectivity and permeation in model sodium channel studied with Dynamic Monte Carlo. ⺠Ion permeation is single ion moving by simple diffusion. ⺠Model reproduces Na+ vs. K+ selectivity, Ca2 + exclusion, DEKA to DEEE mutations. ⺠Na+ vs. K+ selectivity: K+ excluded from crowded pore and moves slower through pore. ⺠Point mutations DEKA â DEEE make calcium channel, reproducing experiments.
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Authors
Ãva Csányi, DezsÅ Boda, Dirk Gillespie, Tamás Kristóf,