Article ID Journal Published Year Pages File Type
10797552 Biochimica et Biophysica Acta (BBA) - Biomembranes 2012 8 Pages PDF
Abstract
►Inhibiting SER Ca2 + pump with thapsigargin blocks Ca2 + entry through NCX. ►There is an increased proximity between the two proteins when SER Ca2 + is depleted. ►A mechanism for the NCX blockade is proposed based on organellar rearrangements. ►This blockade may protect cells from Ca2 + overload when SERCA is not functional.
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Life Sciences Biochemistry, Genetics and Molecular Biology Biochemistry
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