Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797552 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2012 | 8 Pages |
Abstract
âºInhibiting SER Ca2 + pump with thapsigargin blocks Ca2 + entry through NCX. âºThere is an increased proximity between the two proteins when SER Ca2 + is depleted. âºA mechanism for the NCX blockade is proposed based on organellar rearrangements. âºThis blockade may protect cells from Ca2 + overload when SERCA is not functional.
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Authors
Gauri Akolkar, Jyoti Pande, Sue E. Samson, Ashok K. Grover,