Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797608 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 8 Pages |
Abstract
⺠Global biophysical behavior of long chain versus very long chain, and saturated versus unsaturated ceramide species are studied. ⺠Saturated ceramides have a stronger impact on membrane lateral organization. ⺠Ceramide chain asymmetry governs interdigitation independently of the degree of unsaturation. ⺠Ceramide interdigitation is the driven force behind tubular structure formation. ⺠Saturated-ceramide gel domains have a long range effect in increasing the order of the POPC-rich fluid phase.
Keywords
GUVC16-ceramideRho-DOPEt-PnASLSDPHCeramide synthasesCerSMLVPoPCFCS1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine1,6-diphenyl-1,3,5-hexatrienemultilamellar vesiclessphingolipidssphingomyelintrans-parinaric acidInterdigitationRhodamine 110fluorescence correlation spectroscopyGiant unilamellar vesicles
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Biochemistry
Authors
Sandra N. Pinto, Liana C. Silva, Anthony H. Futerman, Manuel Prieto,