| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797613 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 7 Pages |
Abstract
⺠Lipid membrane effects of two cannabinoid agonists, WIN55212-2 and CP55940, are investigated. ⺠DPPC lipid membrane with specific deuterium labels provides extra details for solid state 2H NMR studies. ⺠The cannabinoid agonists induce lipid lateral phase separation and promote microdomain formation. ⺠The cooperative process of the lipid acyl chain C-2H segment may be modulated by the cannabinoids. ⺠The agonists lower the lipid phase transition temperature and modulate the chain order distinctively.
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Authors
Xiaoyu Tian, Spiro Pavlopoulos, De-Ping Yang, Alexandros Makriyannis,