Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797616 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
⺠The Amphipathic-Lipid-Packing-Sensor (ALPS) motif is studied by molecular dynamics. ⺠Trajectories are performed in pure DOPC and in a mixture DOPC/DOG (85:15 molar ratio). ⺠The introduction of DOG in a DOPC bilayer induces packing defects. ⺠ALPS displays more flexibility in a loosely packed membrane. ⺠ALPS lipid packing sensing capability may have an entropic origin.
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Authors
Paula González-Rubio, Romain Gautier, Catherine Etchebest, Patrick F.J. Fuchs,