| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797641 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 7 Pages |
Abstract
⺠We demonstrate that oxy-cholesterol-containing lipid vesicles were more sensitive to temperature. ⺠We show that keto functional group rendered lipid vesicles more thermo-sensitive than OH group at carbon 7. ⺠We show that OH group at C 25 has the same effect as the keto group at C 7. ⺠Characterization of the membrane dynamics provide a new insight into oxidative-stressed membranes. ⺠We show that temperature change in conjunction with membrane oxidation induces membrane instability.
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Authors
Mun'delanji C. Vestergaard, Tsuyoshi Yoda, Tsutomu Hamada, Yoko Akazawa (Ogawa), Yasukazu Yoshida, Masahiro Takagi,