Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797645 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
⺠Simulated symmetrically and asymmetrically arranged melittins in a POPC bilayer pore. ⺠For the first time observed creation of the fully toroidal pore in symmetric arrangement. ⺠Observed that helicity is not a prerequisite for the toroidal pore creation. ⺠Investigated the role of melittin charge distribution promoting toroidal pore creation. ⺠Proposed that the symmetrical arrangement of melittin peptides is more favorable for the toroidal pore creation.
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Authors
Sheeba J. Irudayam, Max L. Berkowitz,