| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797661 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 9 Pages |
Abstract
⺠Critical amino acids of TMVI of the Na+/H+ exchanger were mutated. ⺠TM VI critical residues include Asn227, Ile233, Leu243, Glu247 and Glu248. ⺠Mutant proteins yielded varying defects in activity expression and targeting. ⺠Modeling of TMVI indicates it forms a critical part of the ion conductance pathway.
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Authors
Jennifer Tzeng, Brian L. Lee, Brian D. Sykes, Larry Fliegel,