| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10797672 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 13 Pages |
Abstract
⺠We have carried an exhaustive analysis of the membranotropic regions of DENV C and E proteins. ⺠C protein displayed one highly positive membrane-interacting region. ⺠E protein showed five different membranotropic regions. ⺠These zones should be implicated in the molecular mechanism of membrane fusion, replication and/or budding.
Keywords
MLVegg l-α-phosphatidic acidbovine brain l-α-phosphatidylserine1,2-dielaidoyl-sn-glycero-3-phosphatidylethanolamine5-CarboxyfluoresceinDEPEtrifluoroethanolTFEDSCDENVBPIBPSEPATPECHOLEPCESMmultilamellar vesiclesegg sphingomyelinlarge unilamellar vesiclesegg l-α-phosphatidylcholinetransmembrane domainDengueendoplasmic reticulumMembrane fusionLUVBMPDengue virusNon-structural proteinDifferential scanning calorimetrycholesterol
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Authors
Henrique Nemésio, Francis Palomares-Jerez, José VillalaÃn,