Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10797679 | Biochimica et Biophysica Acta (BBA) - Biomembranes | 2011 | 5 Pages |
Abstract
⺠Mast cell is a key player in allergic responses. ⺠Mast cell secretes inflammatory mediators by SNARE-dependent exocytosis. ⺠We investigated the role of synaptotagmin 2 in exocytosis, using liposomes. ⺠High concentration of synaptotagmin 2 enhanced the SNARE-mediated liposome fusion. ⺠Low concentration of synaptotagmin 2 inhibited the liposome fusion.
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Authors
Yumiko Nagai, Satoshi Tadokoro, Hiroki Sakiyama, Naohide Hirashima,